Garcinia lactone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Garcinia内酯是一种抗肥胖剂。Garcinia内酯是ATP柠檬酸裂解酶的有效抑制剂，该酶催化柠檬酸线粒体外裂解为草酰乙酸和乙酰辅酶A。

Garcinia lactone is an anti-obesity agent.Garcinia lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.

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(-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken. Animal Model:1-day-old male broiler chickens Dosage:1000, 2000, 3000 mg/kg Administration:Fed for a period of 4 weeksResult:Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower.

(-)-Hydroxycitric acid lactone

Endocrinology/Hormones

ATPase

ATP citrate lyase

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27750-13-6

190.11

C6H6O7

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (1315.03 mM)

O[C@@](C1)([C@@H](C(O)=O)OC1=O)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years